Necroptosis: Molecular Signalling and Translational Implications

Necroptosis: Molecular Signalling and Translational Implications

Blog Article

Necroptosis is Holders a form of programmed necrosis whose molecular players are partially shared with apoptotic cell death.Here we summarize what is known about molecular signalling of necroptosis, particularly focusing on fine tuning of FLIP and IAP proteins in the apoptosis/necroptosis balance.We also emphasize necroptosis involvement in physiological and pathological conditions, particularly Blood Pressure Monitors in the regulation of immune homeostasis.